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FAQ
> Glossary of Terms > S Series > Spray
Drying
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Pharmaceutical & Cleanroom Glossary of Terms
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Spray Drying
Process by which a material in suspension is converted into
droplets that may be coated by a substance, either melted
or dissolved in the droplet's media. The action in spray drying
is primarily that of evaporation, energy is applied to the
droplet forcing evaporation of the media with both energy
and mass transfer through the droplet. Examples of this technology
include, pharmaceutical tablet granulation, and rapid drying
which results in free-flowing powders on a continuous basis.
Spray drying process consists of the following steps:
- 1. Formation of a slurry to be sprayed; this slurry may
be a simple concentrated solution or the dispersion of an
insoluble material in a solution.
- 2. Liquid atomization into droplets; this action is critical
as the droplet size will dictate the equipment size as well
as the final product size. There are four types of atomization
devices: air, airless, disk (or rotary) spray, and ultrasonic.
- 3. Exposure of the droplet to a heated gas flow; this gas
(normally air) supplies the energy required to vaporize the
solvent. Collection of the dry free-flowing powder or encapsulated
liquid or solid.
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