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FAQ > Glossary of Terms > R Series > Reverse Osmosis (RO)
 

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Pharmaceutical & Cleanroom Glossary of Terms


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Reverse Osmosis (RO)
RO is one of two acceptable techniques for producing Water For injection (WFI), U.S.P. Procedure involves passing purified water across a semipermeable membrane against an osmotic gradient. R.O. is an excellent pretreatment for deionized water that will be subsequently filtered, because silt and colloids are removed. Usual performance of R.O. is removal of organics, multi-valent ions, and 90% of mono-valent ions

OR

The reversal of osmosis to purify water. In osmosis, water diffuses through a semipermeable membrane from a region of higher concentration (such as pure fresh water) into one of lower concentration (such as a solution of water and salt). The flow of water can be reversed with an opposing pressure that exceeds osmotic pressure. With RO, water is forced out of the lower concentrated solution (such as the salt solution), leaving the solute (impurities) behind.