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FAQ
> Glossary of Terms > R Series > Reagent
Grade Water
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Pharmaceutical & Cleanroom Glossary of Terms
A Series , B
Series , C Series , D
Series , E Series , F
Series , G Series , H
Series , I Series , K
Series , L Series , M
Series , N Series , O
Series , P Series , Q
Series , R Series , S Series
, T Series , U
Series , V Series , W
Series , X
Series , Y Series , Z
Series
Radiation
Sterilization, Radio
Immunoassay(RIA), Radioactive
Material, Raw Material,
rDNA(Recombinant
DNA), Reagent, Reagent
Grade Water, Recalcification,
Recessive Allele,
Recirculation, Recombinant,
Recombinant Clone,
Recombinant
DNA Molecules, Recombinant
DNA Techniques, Recombinant
DNA Technology, Recombination,
Recovery, Recovery
Time, Reference
Standards - Primary, Referential
Integrity, Refrigerants,
Regenerate, Regulatory
Affairs, Regulatory
Region or Sequence, Reject
Stream, Relational
Database Management System(RDBMS), Relative
Humidity(%H), Release,
Renaturation, Representative
Sample, Reproductive
Toxicology, Reprocessing,
Reprocessing(ICH
API Definition), Resin,
Resistance(Filter),
Resolution, Restriction
Enzyme Cutting Site, Restriction
Fragment Length Polymorphism(RFLP), Retest
Date, Retinoblastoma,
Retrospective
Validation, Retrovirus,
Revalidation, Reverse
Osmosis(RO), Reworking,
Ribosomal RNA(rRNA),
Ribosomes, Rickettsias,
Rinse, Roller
Bottles, Rouge, Roughness,
Restriction Enzyme,
Recombinant DNA
(rDNA)
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Reagent Grade Water
Water suitable for use in making up reagents or for use in sensitive
analytical procedures. There are several grades of reagent grade
water as defined by various professional organizations, such as
ASTM, CAP, NCCLS, and ACS:
- 1. Type I: Used for procedures requiring maximum accuracy
and precision, such as atomic spectrometry, flame photometry,
enzymology, blood gas, pH and specific ion determinations;
reference buffer solutions; and reconstitution of lyophilized
materials used as standards. ASTM to produce Type I water
specifies distillation pretreatment of feedwater.
- 2. Type II: Recommended for most analytical or general laboratory
testing such as hematological, seralogical, and microbiological
procedures as well as chemical methods not specifically stated
or proven to require Type I quality. ASTM specifies preparation
of Type II by distillation and recommends it whenever freedom
from organic impurities is important.
- 3. Type III: Satisfactory for some general laboratory tests;
for most qualitative analyses such as urinalysis, parasitology,
and histological procedures; for rinsing of analytical samples;
preparation of stock solutions; and for washing or rinsing
of glassware (final glassware rinsing should be performed
with the water type specified for the procedure performed).
Distillation, mixed-bed deionization, and reverse osmosis
(with high quality feedwater) can be used to generate Type
III.
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