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Material Containment
The method to incorporate suitable measures into design procedures and operational practices for the containment of materials that can harm personnel and the workplace environment, and minimize potential for cross contamination and housekeeping concerns in the fine chemical, bulk pharmaceutical and pharmaceutical industries. Solids and/or liquids are normally most hazardous in the form of powders and have been divided into the following three categories:

1. Biologically Hazardous additives are compounds that when contacting a living cell, will alter, endanger, or damage the cell in some shape or form. These should be treated as requiring total containment.

2. Chemically Hazardous additives are compounds that when coming into contact with an oxidant, will cause harm to its surroundings due to reaction and/or oxidation. These products usually require containment and/or blanketing with an inert gas.

3. General Intermediates are compounds that are neither biologically nor chemically hazardous additives but they will cause a housekeeping problem. They usually require dusting prevention.