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Dead Leg
An area of entrapment in a vessel or piping run that could lead to contamination of the product. In a piping system, a non-flowing pocket, tee, or extension from a primary piping run that exceeds a defined number of pipe diameters from the ID of the primary pipe. Denoted by the term L/D or L/A, where L is equal to the leg extension perpendicular to the normal flow pattern or direction, A is the annular gap width, and D is equal to the ID (or inside dimension) of the extension or leg. In some existing standards, the dimension L is measured from the centerline of the primary pipe. For bioprocessing systems, an L/D of 2:1 is achievable with today's component technology for most valving and piping configurations