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FAQ
> Glossary of Terms > D Series > DNA
Deoxyribonucleic Acid
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Pharmaceutical & Cleanroom Glossary of Terms
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D5W(5 D/W),
Dalton, Data
Integrity, Data
Migration, DDC(Direct
Digital Control), D Value,
Dead Leg, Decontamination,
Deflagration,
Degrading, Deionization,
Deletion Map, De
Minimis Release, Dementia,
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Earth Diatomite(Kiselguhr(DE)), Diffusion,
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Factor, Diploid, Diplophase,
Direct Impact
System, Disaster,
Discoloration(Welding),
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Solids, Distillation,
DNA(Deoxyribonucleic Acid), DNAse(Deoxyribonuclease),
DNA Arrary, DNA
Replication, DNA
Sequence, DNA Vector,
Domain, Dominant
Allele, DOP(Dioctyl
Phthalate/Dispersed Oil Particulate), Dosage
Form, Dosage Group,
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(Medicinal) Product, Durability,
Dry Air, Dry
Heat Sterilization, Dust,
Dynamic Condition
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Cancer Mesothelioma due to Asbestos Exposure, it can affect
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DNA (Deoxyribonucleic Acid)
The molecule of which the genetic material is composed. It
consists of two chains joined together as a double helix.
Each chain is composed of a polymer of nucleotides (consisting
of a nitrogenous base, a deoxyribosesugar ring, and a phosphate
group) joined together by phosphodiester bonds between the
5'-phosphate of one nucleotide and the 3'-hydroxyl of the
next. The two chains run in opposite directions and are held
together by hydrogen bonds between the bases in equivalent
positions in the two chains. There are various forms of double
helical DNA. They are:
- 1. B-DNA (first described by Crick and Watson) is a right-handed
helix with 10.6 base pairs per turn and is probably the main
form of cellular DNA
- 2. A-DNA is also a right-handed helix but is somewhat skewed
and contains about 11 base pairs per turn. It is the form
taken By DNA-RNA hybrid double helixes
- 3. Z-DNA is a left-handed helix with 11 base pairs per turn.
It is favored by regions rich in guanine cutosine base pairs
and probably occurs infrequently in cellular DNA
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