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FAQ
> Glossary of Terms > C Series > Cell
Fusion
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Pharmaceutical & Cleanroom Glossary of Terms
A Series , B
Series , C Series , D Series
, E Series , F
Series , G Series , H
Series , I Series , K
Series , L Series , M
Series , N Series , O
Series , P Series , Q
Series , R Series , S
Series , T Series , U
Series , V Series , W
Series , X
Series , Y Series , Z
Series
Calcium,
Calcium
Carbonate Equivalent, Calibration,
Calibration(ICH
API Definition), Calorie,
Calorimetry, Cancer,
Capsid, Carbohydrates,
Carbon Filter, Carbon
Thickness, Carbonate
Hardness, Carcinogen,
Carrier, Catabolism,
Catalase, Catalyst,
Cation, Cation
Exchange, Cation
Exchange Resin, Cavitation,
Centre
for Biologics Evaluation and Research(CBER), Centre
for Drug Evaluation and Research(CDER), Certified
Vendor Drawings, Celsius,
Cell, Cell
Bank, Cell Culture,
Cell Differentiation,
Cell Fusion ,Cell
Lines, Cellulose,
Centimorgan(cM),
Centrifugation,
Centrifuge, Sedimenters,
Centromere, Certification,
CFR(Code
of Federal Regulation), CFU(Colony
Forming Unit), cGMPs(Current
Good Manufacturing Practices), Change
Control, Change Over,
Channeling, Characterization,
Checksum, Chelating
Agents, Chemoautotrophs,
Chemostat, Chemotheraphy,
Chimeric, Chloramine,
Chlorinated Vinyls,
Chlorination, Chlorine,
Chlorine Demand,
Chlorine Residual,
Chloroplasts, CHO(Chinese
Hamster Ovary) Cells, Chromatids,
Next 60 - 120 Words,
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120 - 175 Words
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Cell Fusion
The fusing together of two or more cells to become a single cell.
This technique has had important consequences in immunology, developmental
biology, and genetics. For example, monoclonal antibodies are
produced by fusing a spleen cell (producing an antibody specific
for the antigen of interest) with a mouse myeloma cell to produce
a hybridoma which has an indefinitely long life because of the
myeloma component and which secretes a specific antibody. When
a human cell is fused with a mouse cell, the human chromosomes
are progressively lost from the resultant hybrid and by correlating
the presence of proteins in the hybrid with the presence of particular
human chromosomes, genes can be assigned to individual chromosomes
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