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FAQ > Glossary of Terms > C Series > Cell Fusion
 

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Calcium, Calcium Carbonate Equivalent, Calibration, Calibration(ICH API Definition), Calorie, Calorimetry, Cancer, Capsid, Carbohydrates, Carbon Filter, Carbon Thickness, Carbonate Hardness, Carcinogen, Carrier, Catabolism, Catalase, Catalyst, Cation, Cation Exchange, Cation Exchange Resin, Cavitation, Centre for Biologics Evaluation and Research(CBER), Centre for Drug Evaluation and Research(CDER), Certified Vendor Drawings, Celsius, Cell, Cell Bank, Cell Culture, Cell Differentiation, Cell Fusion ,Cell Lines, Cellulose, Centimorgan(cM), Centrifugation, Centrifuge, Sedimenters, Centromere, Certification, CFR(Code of Federal Regulation), CFU(Colony Forming Unit), cGMPs(Current Good Manufacturing Practices), Change Control, Change Over, Channeling, Characterization, Checksum, Chelating Agents, Chemoautotrophs, Chemostat, Chemotheraphy, Chimeric, Chloramine, Chlorinated Vinyls, Chlorination, Chlorine, Chlorine Demand, Chlorine Residual, Chloroplasts, CHO(Chinese Hamster Ovary) Cells, Chromatids, Next 60 - 120 Words, Next 120 - 175 Words


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Cell Fusion
The fusing together of two or more cells to become a single cell. This technique has had important consequences in immunology, developmental biology, and genetics. For example, monoclonal antibodies are produced by fusing a spleen cell (producing an antibody specific for the antigen of interest) with a mouse myeloma cell to produce a hybridoma which has an indefinitely long life because of the myeloma component and which secretes a specific antibody. When a human cell is fused with a mouse cell, the human chromosomes are progressively lost from the resultant hybrid and by correlating the presence of proteins in the hybrid with the presence of particular human chromosomes, genes can be assigned to individual chromosomes