If a biological material is spilled on a person, emergency response is based on the hazard of the biological agent spilled, the amount of material spilled, and whether significant aerosols were generated. If aerosol formation is believed to have been associated with the spill, a contaminated person shall leave the contaminated area immediately. If possible, (s)he should go to another laboratory area so that hallways and other public areas do not become contaminated.

Contaminated clothing is removed and placed in red or orange biohazard bags for disinfecting. Contaminated skin shall be flushed with water and thoroughly washed with a disinfectant soap. Showering may be appropriate, depending on the extent of the spill.